中药对股骨头坏死修复愈合机制的探讨

　　摘　要：本文进行了18只兔股骨头坏死用生脉成骨胶囊治疗后股骨头修复的生物力学性能、生化和电镜分析，探讨中药对股骨头修复愈合机制，探索骨骼重建理论，应力与骨愈合生长作用机理性研究，以此论证中药“生脉成骨胶囊”有促进骨坏死修复的作用。

　　A STUDY ON REPAITING MECHANISM OF THE FEMORAL HEAD MECROSIS TREATED WITH CHINESE HERB

　　he Wei,Yuanhao,Fangbin(The hip center of the first affiated hospital of Guangzhou university of TCM 510405)

　　Abstract：To investigate the repairing mechanism of necrotic femoral head treated with Shengmai Chenggu capsule, we measured the mechanical properties and biochemical components of steroid-induced necrosis of femoral head in the rabbits. The results revealed the mechanical properties osteocalcium, the ratio of Ca/P and collegen of the femoral head in the group treated with Chinese herb were better than those in the group control and model. It indicated Shengmai Chenggu capsule can modify biochemistry metabolism, improve necrotic bone repairing

　　Keywords：Femur head necrosis, Shengmai Chenggu capsule, Biomechanics, Biochemistry, Electron microscope参考文献：

　　［1］Fung YC，Biomechanical-mechanical Properties of living tissues．Springer．New york，1993：PP．187～319．

　　［2］Cowin．SC．Biomechanics study of Bone，Applied physiological Mechanics．1979, PP．143～180．

　　［3］袁浩、何伟．生脉成骨胶囊治疗股骨头坏死后的股骨生物力学特性研究．医用生物力学．2000；15：1．P58．

　　［4］王以进编著，生物组织各向异性弹性力学．上海．上海科技大学出版社．1989：PP．126～130．

　　［5］Reilly TD，An Experimental Study Of mechanical properties of femoral fead．J．Biomechanics．1979．vo1.8：PP．303～405．

　　［6］王以进，曲克服．实验性动物骨折愈合过程的生物力学特征，上海科技大学学报．1984．4：P89～96．