Sutherland HJ,et al.Alternative mechanisms with and without steel factor support primitive human hematopoiesis,Blood,1993;81:1465
Lansdorp PM,et al.Ontogeny-related change:in proliferative potential of human hematopoietic cells.J Exp Med,1993;178:787
Metcalf D,Hematopoietic regulator:redundancy or subtlety?Blood,1993:82:3515
Heimfied S,et al.Ex vivo expansion analysis from CD34+ HLA-BRI,CD34± and CD38+subest Eep Hematol,1994(Abstr):22:756
Bjomson BH.et al.Inhition of CFU-NM and CFU-Eos by matrure granulocytes,Blood,1984:63:376
Tavassoli M,Hematopoetic survival factro.Exp Hematol,1993;21:1411
Moore MA,Expansion of myeloid stem cells in culture.Semin Hematol,199:32:183
Haylock ND,et al.Ex vivo ecpansion and maturation of peripheral blood CD34+ cells into the myeloid lineage ,Blood,1992;80:4405
Sato Net al.vitro expansion of human peripheral blood CD34+cells,Blood,1993;82:3600
Brugger W,et al.Ex vivo ecpansion of enriched perpheral blood CD34+ progenitor cells by stem cell factor,interleukin-1 beta(IL-1 beta),IL-6,IL-1,interferon-gamma,and erythropoietin Blood,1993:81:2579
Mayani H,et al.Cytokine-induced selectiver expansion and maturation of erythroid versus myeloid cord blood precurrsor cell.Blood,1993;81:3252
Nakahata T,Expansion of hematopoietic progenitors.In:Bajus JL,et al.eds,Education Program of The 26th Congress of The Intemational Society of Haematology Singapore,1996;29-302
Osyka T et al.The effects of interleukin-6 and interleukin-3 on early hematopoietic events in long-term cultures of human marrow,Exp Hematol,1991;19:1042
Koller MR,et al.Long-term culture initiating cell expansion is dependent on frequent medium exchange combined with stromal and other accessory cell effects .Blood,1995;86:1784
Koller MR,et al.Expansion of primitaive human hematopoietic progenitors in a perfusion bioreactor syystem with IL-3,IL-6 and stem cell factor.Biotechnology,1993;11:358
Han CS,et al.In vitro expansion of umbilcal cord blood committed and primitive progenitors.Exp Hematol,1994(Astl):22:723
Verfaillie CM,Direct contact between human primitive hematopoieitc progenitors and bone marrow stuoma is not requied for long-term in vitro hematopoiesis,Blood,1992;79:2821
Guba SC,et al.Bone marrow stromal cells secrete IL-6 and GM-CSF in the absence of inflammatory stimuli:demonstration by serum-fred bioassay:ELSA,and reverse transcriptase polymerase chair,reaction,Blood,1992;80:1190
Schwartz RM,et al.Rapid medium perfusion rate significantly increases the productivity and logevity of human bone marrow cultures.Proc Natl Acad Sci USA,1991;88:6760
Palsson MA,et al.Expansion of CD34+-enriched human bone marrow cells:effct of heeding schedule schedule cytokines and stuoma.Exp Hematol,1994(Abstr):22:726
Koller RM,et al.Reduced oxygen temsion increases hematopoiesis in long-term culture of human stem and progenitor cells from cord blood and bone marrow.Exp Hematol,1992:20:264
Palsson BO,et al.Expansion of human bone marrow progenitor cells in a high cell desity continuous perfusion system.Bio-Technol,1993;11:368
Davis TA,et al.Large scale expansion of human CD34+ progentor cells on porcine endothelial cells in and artifical capillary system,Exp,Hematol,1994(Abstr):22:803