neurodegenrative effects of βamyloid and protection by substance P,Proc Natl Acad Sci USA,1991,88(16):7274
Wade R,New lesion fornd in diseased brains .Science,1997,277:31
Ben-Ari Y,Tremblay E,Ottersen OP,et al.The role of eplieptic activityin hippocampal and remote cerebral lesions induced by kainic acid.Brain Res,1980,191:79
Sofroniew MV,Pearson RCA,Degeneration of choliergic neurous in ghe basal nucleus following kainic or N-methyl-D-aspartic acid application to the cerebral cortex in the rat.Brain Res,1985,339(1)1:186
Hastings MH,Winn P,Dunnett SB,Neurotoxic amino acid lesions of the lateral hypothalamus:a parametric comparison of the effects of ibteate.N-metyl-D L-aspartate and quisqualalate in the rat.Brain Res,1985,360:248
Dunnett SB,Whishaw IQ,Jones GH,et al.Behavioural,biochemical and histochemical effects of different neurotoxic aminoacids injected into nucleus basalis magnocellularis of rats.Neuroscience,1987,20(2):653
Coyle J,Mckinney M,Johnston M,et alSynaptic neurochrmistry of the basal forebrain cholignergic projection.Psychopharmacol Bull,1993,19:441
Wenk G,Olton D,Recovery of neocortical choline acetyltrans-ferase activity following iboteic acid injection into the nucleus baalis of Meynert in rats.Brain Res,1984,293:184
郑观成，脑老化与老年痴呆，第一卷,第1版，上海，上海科学技术文献出版社，1994，127
Mantione CR,Zigmond MJ,Fisher A,et al.Selective lesioning of rat hippocampal cholineergic neurons following localized injection of AF64A,J Neurochem,1983,41:251
Arbogast RE,Kozlowski MR,Reduction of cortical choline acetyltransferase activity following infections of ethlcholine mustard aziridinium ion(AF46A)into the nucleus basalis of Meynert,Soc Neurosci Abstr,1984,10:1185
Wiley RG,Berbos TG,Deckwerth TL,et al.Destruction of the cholinergic basal forebrain using immunotoxin of Alzheimer's diseases.J Neurol Sciences,1995,128:157
Gary LW,James DS,George Q,et al.Behavioral ,biochemical,histological ,and electrophysiolgical effects of 192 IgG-saporin infections into the basal forebrain of rats.J Neurosci,1994,14(10):5986
宋前流，宋瑞义，参归煎剂抗痴呆作用与谷氨酸的关系，中成药，1995，17（6）：28
Stone TW,Perkins MN,Quinolinic acid:A potent endogenous excitant at amino acid reeptors in CNS,Eu J Parmacol,1981,72;411
Caulfield MP,Fortune DH,Rowvrts PM,et al.Intracere-broventricular hemicholinium-3(HC-3) impairs learning of a passive avoidance task in mice,Bri J Pharmaco,1981 ,74(4):865
Bartus RT,Dean RL,Beer B,et al.The choliergic hypothesis of geristric memory dysfunction .Science,1982,217(4558):408
秦俊法,微量元素与脑功能,第1版,北京,原子能出版社,1994,52
李文彬,张炳烈,马向晨等.吡乙酰胺对三氯化铝中毒大白鼠回避反应受损的对抗作用.中国药理学与毒理学杂志,1988,2(2):132
Perl DP,Brody AR,Alzheimer disease X-ray spectrometric evience of aluminum accumlation in neurofibrillary tanglebearign neurons .Science,1980,208(18):297
刘成铮,陈光,途格晟,等.Alzheimer型老年性痴呆与铝的关系.临床神经病学杂志,1994,7(1):37
胡海涛,钱亦华,杨杰，等.淀粉样前体蛋白在痴呆模型大鼠背海马结构的表达,解剖学杂志,1997,20(5):444
钱亦华,杨杰,任惠民,等.痴呆模型大鼠背海结构内淀粉样蛋白沉积的免疫细胞化学研究,西安医科大学学报,1997,18(30:304
Gage FH,Bjorkund A,Stenevi U,Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents.Brain Res,1983,268:27
Dunnett SB,Neural transplantation in animal models of dementia.Eur J neuroaci,1990,2:567
Jeltsch H,Cassel JC,Neufang B,et al.The effects of intahip-pocampal taphe and/or septal grafts in rats with fimbria-fornix lesions depend on the grafted tissue and the behavioural task used .Nueroscience,1994,63(1):19
Quon D,Wang Y,Catalano R,et al.Formation of β-amyloid protein deposits in brains of transgeoic mice .Nature,1991,352:239
孙延昌摘译,Alzheimer 病的动物模型,国外医学(老年医学分册),1996,17(3):80
Robertson M,Alzheimer's disease and amyloid. Nature,1992,356:103
