目前所存问题及研究前景
嗅觉系统的解剖复杂，深层嗅觉中枢的具体定位尚无定论。嗅觉生理具有特殊性，许多理论和技术问题（如嗅觉系统与三叉神经系统之间的关系，刺激气的数量、强度和频率的控制等）尚待解决。嗅性诱发电位各波的具体来源及其与疾病间的相互关系还不清楚，目前尚不能用于嗅性系统疾病的定位、定性诊断。
但是，越来越符合自然嗅机制的刺激器不断研制产生，嗅觉通路的解剖和嗅觉生理正在不断得到阐明。随着对嗅性诱发电位研究的不断深入，它必将得到更加广泛的应用。另外，CT、MRI等影像学检查主要反映组织结构的改变，而嗅性诱发电位主要用于反映感觉径路功能和大脑高级中枢的认知水平，两者相互结合，必将大大提高临床诊断及病情预估的质量。且已有研究表明，应用嗅性诱发电位检查嗅觉障碍比应用主观的嗅觉功能检查方法更灵敏［13,19,20］。
综上所述，嗅性诱发电位作为一项客观而灵敏的电生理指标，具有广阔的科研前景和重要的临床应用价值。
作者单位：陈兴明 北京 中国医学科学院中国协和医科大学北京协和医院耳鼻咽喉科 100730
徐春晓 北京 中国医学科学院中国协和医科大学北京协和医院耳鼻咽喉科 100730
倪道凤 北京 中国医学科学院中国协和医科大学北京协和医院耳鼻咽喉科 100730
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